The information on this website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified healthcare professional regarding any medical questions or conditions.

What is H. pylori?

Helicobacter pylori (H. pylori) is a type of bacteria that lives in the lining of the stomach or duodenum1 (the beginning of the small intestine). Two-thirds of the world's population is infected with H. pylori.2 In the United States it is more common in older adults; about 30% of 50 year olds have H. pylori living in their gastrointestinal system.3

Most Americans never know if they have H. pylori because they never develop symptoms serious enough for them to see their physicians. However, in others, infection with H. pylori can cause gastro-intestinal issues, including ulcers in the stomach and duodenum.2

In the past, we thought that spicy food and emotional stress were the major causes of ulcers. We now know that 9 out of 10 ulcers are caused by H. pylori infection.1

It is not known how H. pylori is transmitted or why some people develop symptoms while others do not.2 Now that scientists know that most ulcers are caused by H. pylori, this can be treated with the right therapeutic regimen.1

Peptic ulcer disease is a term used to describe upper gastrointestinal ulcers located in the stomach (gastric ulcer) and duodenum (duodenal ulcers).4 Approximately 25 million Americans suffer from peptic ulcer disease at some point in their lives.1 Fortunately, there are effective treatments available to treat the underlying cause of ulcers and to reduce the likelihood of an ulcer recurring.1 PYLERA® is one such treatment, that in combination with omeprazole, is used to treat patients with H pylori infection and duodenal ulcer disease.


  • pregnant* or nursing women
  • pediatric patients under the age of 8
  • patients with kidney or liver problems
  • patients with hypersensitivity to bismuth subcitrate potassium, metronidazole or other nitroimidazole derivatives, or tetracycline

* Notify your doctor immediately if you become pregnant while taking PYLERA®

Information on this website is not intended to replace the advice of your physician(s). Please consider what you learn here a starting point for a conversation with your physician. PYLERA® is a prescription drug; please ask your physician if PYLERA® is right for you.

1. Helicobacter pylori and Peptic Ulcer Disease. Centers for Disease Control and Prevention Website, Division of Bacterial Diseases. Available at: Accessed 12/3/09 2. Helicobacter pylori and Peptic Ulcer Disease: the Key to Cure. Centers for Disease Control and Prevention Website, Division of Bacterial Diseases. Available at: Accessed 12/3/09 3. Yamada, T. Handbook of Gastroenterology: Second Edition. Lippincott Williams & Wilkins 2005; 264-265. 4. What I need to know about Peptic Ulcers. National Institute of Health Consumer Website. Available at: Accessed 12/3/09